110P Changes of Serum Vitamin D According to the Breast Cancer Treatment

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Prediagnostic serum vitamin D and breast cancer.

The active metabolite of vitamin D [i.e., 1,25(OH)2D] is a recognized modulator of cell proliferation and differentiation (1,2), and studies (3) have shown that it can reduce the incidence of mammary cancer in rats. Several mechanisms have been postulated for a protective effect of vitamin D on human breast cancer (3–8); however, epidemiologic studies (9–17) investigating dietary sources of vit...

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Serum vitamin D and breast density in breast cancer survivors.

BACKGROUND Vitamin D influences cellular proliferation and proliferation-related breast tissue characteristics, such as mammographic breast density. Little is known about vitamin D status, assessed by serum 25-hydroxyvitamin D [25(OH)D], and its relationship to breast density in breast cancer survivors. METHODS Participants were 426 postmenopausal breast cancer survivors from the Health, Eati...

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Meta-analysis: serum vitamin D and breast cancer risk.

We reviewed and summarised observational epidemiological studies regarding the association between serum vitamin D (measured as 25(OH)D levels) and the risk of breast cancer (BC). Relevant studies published until September 2009 were identified by systematically electronic searching Ovid Medline, EMBASE and ISI Web of Knowledge databases and by cross-referencing. The following data were extracte...

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Vitamin D and breast cancer.

In addition to its role in calcium homeostasis and bone health, vitamin D has also been reported to have anticancer activities against many cancer types, including breast cancer. The discovery that breast epithelial cells possess the same enzymatic system as the kidney, allowing local manufacture of active vitamin D from circulating precursors, makes the effect of vitamin D in breast cancer bio...

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2012

ISSN: 0923-7534

DOI: 10.1016/s0923-7534(19)65771-6